Glove Box Isolator

Laboratory Equipment Manufacturing

Bionics Consortium Pvt. Ltd.

In a laboratory glove box, we maintain a sterile air environment by continuously clearing and replacing filtered air. This allows us to conduct sensitive operations without interference from other activities. Laboratories and pharmaceutical manufacturers employ glove boxes for various purposes.

When transacting business within a glove box, one normally wears sterile gloves and gowns. They fit the box firmly and have sleeves that ensure there is a tight fit gloves in the box. This effectively seals the box without side elements that can pollute the air within the box.

Laboratory glove boxes are popular in research and industry, R&D, medical/pharmaceutical, and energy/nuclear. They are helpful in obtaining a restricted or enclosed environment. Which is a prerequisite for many processes, such as testing or working with delicate or hazardous substances.

Shielding from external air and all contamination maximizes product protection and ensures the best outcomes for the operator. In many situations, researchers and technicians use glove boxes to handle potential risks. For specific tools or components, and conducting comprehensive operations.

Scientists commonly use laboratory glove boxes to shield samples from light, microorganisms, and other environmental conditions within small, sealed chambers. That is why acrylic laboratory glove boxes provide the desired atmosphere. This does not affect the substance and may include chemicals, biological samples, or electronic components. The box is usually designed with handles or flip-up compartments, and gloves are located on its body. This design allows researchers to interact with objects inside without violating aseptic protocol.

Glove Box Manufacturers, Suppliers and Exporters in India

Bionics Consortium is the top glove box manufacturer in India.

In laboratory analysis, adhering to safety rules requires the use of a high-quality glove box. As for the filter housing, it is highly advisable to pay a lot of attention. When choosing the manufacturer or supplier of reliable containment enclosures. The Bionics Consortium, based in Delhi, is regarded as a global reference by containment technology specialists.

Bionics Consortium has designed and manufactured glove boxes, isolators, gas purification units, and other containment systems over the last several decades. It dedicates its products to many sectors: pharmaceutical-medical, nuclear, aeronautics, industry, R&D, energy, etc. It provides standard laboratory glove boxes for conventional processes. This specialist also offers modular glove boxes to his or her clients. They have the advantage of being customizable, allowing users to set specific values at which the deterioration rate should alert them. Additionally, designers can incorporate accessories into the design as needed.

For this reason, on some occasions, it is possible to require the help of an expert to devise a laboratory glove box that would suit a given project uniquely. In this case, you can also contact Bionics Consortium; its design office may propose a safety device according to the risk classes.

Laboratory glove boxes for safe material handling

In laboratory experiments, researchers commonly use glove boxes when handling radioactive substances or other hazardous chemicals. In a pharmaceutical production facility, you may use it for packaging and labeling operations. The first isolator box provides the inert gas atmosphere for glove boxes. It is necessary to maintain the sterility of the products.

In addition to aeration, glove boxes can also regulate temperature and humidity inside the enclosure. This is important where environmental conditions have to be controlled. For instance, assembling electronic products with small components or handling biological products.

Probably everyone who has something to do with various fields of science is familiar with the use of glove boxes. If there is a glove box, you can work with different materials that are sensitive to the air in the surrounding environment.
A glove box is a sealed compartment in which you can work with various air-sensitive materials or samples without contaminating them with the surrounding air.
We make every effort to keep the glove box airtight and prevent contact between the samples inside and the external environment. Typically, we maintain the glove box with an inert gas to ensure that it does not interact with the materials inside.

The researcher uses the glove box gloves incorporated into the walls of the box to handle the contents of the box. Items, such as materials and equipment, can be transferred into or out of the glove box. Through an intermediate chamber situated between the glove box and the air.

Glove boxes are available in different sizes for usage, ranging from benchtop uses (Bionics Consortium Glove Box) to those with elaborate filters. Manufacturers usually construct them with sturdy metals like steel and may include a glass wall. Through which the researchers can observe what they are dealing with. Typically, designers use acrylic or tempered glass in their construction. The gloves themselves typically use butyl rubber to provide a good grip and minimize leakage around the fingers.

Types of Glove boxes

The containment A laboratory glove box is an enclosed chamber with ports for gloves. This design allows operators to be shielded from the materials contained in the box. While still being able to manipulate them through the glove ports. Glove boxes are useful for tasks such as handling radioactive materials, working with hazardous reagents and solutions, and conducting contact-free experiments under strict aseptic conditions. These glove boxes come with an air change through a HEPA or ULPA filter to maintain the internal environment of the box.

Isolation Glove boxes are a diverse approach to choosing a glove box. If you want to shield the operator from the outer environment, use this type of glove box. There are lots of sizes to choose from, and the boxes can also be equipped with a specified type of ventilation system.

The choice of construction materials for laboratory equipment, include:

ABS plastic for primary chemical resistance
For better chemical and heat resistance, there has been the use of polycarbonate.
Such as PVC or Teflon-coated materials, where the chemicals being stored are more aggressive.
Stainless steel where the autoclave is not compatible or other rigorous environmental requirements.
Aluminum for the regulation of ESD (Electro Static Discharge).
Leads to protection from radiation

With combination boxes, it becomes possible for you to establish both a closed and an open-loop system. This means that they can be employed for very basic operations. Where it is only required that one switch is on. While the other is off or for fairly complex systems where certain inputs are required in the circuit. Combination boxes are suitable for almost all types of projects due to the versatility they offer.

For instance, the anaerobic chamber, which is in fact an enclosed space that is used purposely to lead to an atmosphere free of oxygen. The major uses of anaerobic chambers include things like handling bacteria or any other microorganisms that cannot withstand oxygen exposure.

Containers can vary in material, with stainless steel being commonly used in various grades, notably 304 and 316. The choice of stainless steel depends on the chemicals used and the operating temperature of the equipment.

Size of the laboratory glove box

Glove box size depends on the kind of project you intend to perform, and therefore you have to make a choice depending on your project. If one is doing a small project or not so frequently crushing, a benchtop version may be adequate. It is possible that for a major project, you may need a floor-standing model. You can also use a portable version in case of field research or in a place that does not have a permanent set-up for glove box operations.

Functions of Laboratory Glove Boxes

As for the interior of the containers, it might be possible to set up changing areas according to the specifics of the ongoing work. For instance, nitrogen or argon gas can be used in handling to prevent the oxidization of sensitive materials.

The most common gases used in glove boxes are:

Nitrogen
Argon
Helium
Hydrogen
Carbon dioxide
Methylene chloride
Ethanol

All of these can be utilized in various ways to foster the intended impact. For instance, working in an environment with increased nitrogen concentrations will go a long way toward preventing fire outbreaks. We can also apply negative pressure in order to avoid contamination of the box.

A swing pump is employed to draw a vacuum into the pressure control system with a variable rate of gaseous inflow. This ensures that a constant pressure is maintained inside the box, which is crucial to avoiding any spilling of the delicate materials filled inside the box.

One must ensure that all points are leak-tight to make the glove box perfectly safe and efficient. All connections, arrangements, and interfaces of the gloves to the ports and the ports to each other and the environment must be tight to avert the loss of any form of gas or liquid.

Glove boxes come in various shapes and sizes, but they all serve the same purpose: to create conditions that isolate the working area and some tasks that require more protection than others. The following are some methods of maintaining low relative humidity: In cases of high relative humidity, it is possible to use desiccators to reduce the humidity of the air meant for a certain process. With respect to the procedure described that concerns achieving standard low RH, it will suffice to use a regular glove box equipped with an activated carbon filter.

Standard Laboratory Glove Box Features:

Constructed of 1/4 acrylic material. A clean, inert material that will not outgas plasticizers that can contaminate sensitive components.
8″ diameter glove port.
Back: removable back wall for easy access and maintenance. It is useful for placing and removing larger objects.
Left Side: 10″ x 10″ Access Door
Right Side: The removable panel gives you the option to add a pass-through chamber at any time.
Continuous stainless steel door hinges, providing maximum support.
Recessed, closed-cell neoprene door gaskets and spring-loaded latches form an air-tight door seal.
Heavy-duty, durable construction.

Main Uses of Laboratory Glove Boxes

Laboratory Glove boxes are hermetic boxes made of stainless steel that provide a transparent working face, handling gloves, control and regulation units, and sophisticated transfer and purification systems. They enable the manipulation of goods with conveying properties that should not interact with the surrounding air or transfer into the environment.

Components of a Glove Box and Their Roles

Components of a glove box play a specific role in ensuring its proper functioning:

Main Chamber: The major compartment of a laboratory glove box is the work zone for the operators. All manipulations are performed within this contoured, hermetic protection cell, so to speak. The design of the work table should have one to several transparent working surfaces in order so that the work can be viewed during transfer from one stage to another.

Protective gloves: They are fixed directly on the support rings to the working face of the equipment that relates to their use. Besides personal protection, the operator must protect his hands with protective gloves since he handles samples, products, materials, and compounds.

One to several Transfer Airlocks: At least one of the system’s transfer lockers should be provided in a laboratory glove box. The most expensive glove boxes have more than one. This rather complicated system is necessary if products or instruments must be brought into the main chamber. It ensures that there is no moment when there is a lack of containment. On some of the glove boxes, it is recommended that there be an inlet airlock and an outlet airlock.

Sensors and Regulators: Thus, each project may require the use of various substances or materials. Presumably, based on the requirements required for the treatment of relevant materials, the composition of the gloves can be varied. These include control of pressure and temperature, among other factors, with the help of regulators. Humidity and oxygen level monitoring are done with the help of sensors.

Automatic Safety Flow Rate

Requirements for automatic safety flow are met only in the case of glove boxes intended for personnel protection. It corrects for any pressure drop to contain a leak or a break in containment by design, be it the tearing of a glove or something similar; hence, it provides the highest level of safety. Therefore, the confinement of the atmosphere cannot escape from the enclosed area.

It is fully protective and isolated with an environmental setting lower or higher than the standard pressure belonging to the particular laboratory glove box. People who work in the operator position can execute their work safely. Safety alerts are generated automatically in the event of anomalies.

You can, for instance, use a laboratory glove box when working with volatile, toxic, or radioactive substances, pathogens, active ingredients, materials that are sensitive to the surrounding air, etc. This way, the number of gloves or cuffs and the wall’s transparency allow the operator to work calmly.

Different Types of Laboratory Glove Boxes

The functions of the laboratory glove box include protecting the product, the operator, and the environment. There are two main types:

Containment of dangerous substances

There are specialized laboratories. Glove boxes to accommodate hazardous substances like radiation and germs, just to mention a few. Each protective component of its systems—filters, gloves, airlock, and the manner in which it functions—guarantees adequate protection to exclude the dangers arising from external pollution.

Originally, in nuclear processes where contamination or radiation is harmful to the operators,, there were prerequisites such as filters, lead protection, and lead-charged gloves. For biological or pharmaceutical purposes, the enclosure enables the protection of pathogens. They spoke of upgrading the filter to HEPA H14 to improve safety.

Containment in an inert atmosphere

Creating a nearly perfectly inert environment of truly high purity is the kind of laboratory glove box this invention brings about. To do this, all the various gases and moisture in the form of water and solvents are expelled from the chamber through various integrated units. It is also pressurized to avoid leakage of contaminants into the environment in cases of small leakages, which are employed when operating with argon, nitrogen, or any other pure combinations.

It is mandatory for a laboratory glove box user undergo some form of training. This is the minimum that is required. This is a situation where knobs, extensions, or any other accessories can be added to ease the maneuvering of the equipment. Also, it would be appropriate to comprehend that the use of personal protective gear and the constant readiness of emergency equipment also do not constitute a small part of the general safety measure plan.

Why would you need a glove box?

In general, the primary function of a glove box is to provide a working environment that is isolated and controlled for your tasks. Glove boxes can be unvaluable if you are:

Lab Handling and Storage of Oxygen/Moisture-Sensitive Items Most samples and a good number of chemical reactions cannot come across oxygen or moisture if they are to remain as good as new. Glove boxes enable you to manipulate these materials without presenting them to the atmosphere.
Hazardous Substance Isolation – Some of the Glove boxes have features that help in isolating hazards such substances that may cause harm once in the workplace or laboratory. This safeguards the researcher from physical harm or accidents and also shields the environment from further distractive areas from being invaded by the researcher. These are commonly known as isolation glove boxes.
Contamination Prevention: A glove box can also shield a sample or a particular experiment from elements such as dust or moisture from the outside environment. This is especially important for items such as semiconductors, protein crystallization, and other exact operations. These glove boxes are referred to as contamination glove boxes.

Concisely, glove boxes allow researchers the latitude of setting up the exact conditions around their work to preserve their contents or the reverse—the outside world. This makes them an essential facet in numerous modern technological, advanced, and progressive research areas.

What safety features should one consider when selecting a laboratory glove box?

Material Compatibility: The materials inside the glove box must suit the contents being handled. Some chemicals can contaminate certain substrates or pose safety risks.
Glove Material: For additional chemical resistance, it should be of good quality, like butyl, neoprene, or latex. They should also fit well and provide the wearer with flexibility in handling delicate operations.
Inert Atmosphere: Some glove boxes offer an inert environment, normally using gases. Such as nitrogen or argon, which makes them avoid interactions with oxygen. Ensure that you keep adjusting the glove box so that it gives the desired atmosphere most of the time.
Air Filtration System: Proper air circulation and purification play a critical role towards the achievement of the proper hygiene inside the glove box. While securing the products contained within it. This system should filtrate out small particles so as not to interfere with experiments or harm the workers.
Pressure Control: The glove box should include provisions for controlling internal pressure leakage and ensuring the kind of containment. Pressure control systems can be efficient in maintaining adequate pressure levels in the equipment.
Leak Detection: Installation of leak detection systems helps in detecting any breakages in the glove box. This helps prevent any exposure to toxic compounds.
Emergency Stop Mechanism: A clearly labeled emergency stop mechanism should be easily accessible to quickly shut down glove box operations in case of emergencies or malfunctions.
Access Ports and Interlocks: Access ports with interlocks help prevent accidental exposure to hazardous materials. By ensuring that the glove box can only be accessed when it is safe to do so.
Fire Suppression System: In case of fire or ignition within the glove box, a fire suppression system can quickly extinguish flames to prevent spreading and minimize damage.
User Training and Safety Procedures: Comprehensive user training and clear safety procedures are essential for the safe operation of a glove box. Users must be educated on proper handling techniques, emergency protocols, and the potential hazards associated with the materials they are using.
Ergonomic Design: A well-designed glove box should consider ergonomic factors to minimize user fatigue and discomfort during prolonged use. Thereby reducing the likelihood of accidents.