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HEPA Filtration Glove Box

Laboratory Equipment Manufacturing

The use of filtration glove boxes in closed system environments serves to safeguard the sensitive materials and those who handle them from any form of contamination.

These boxes are applied in industries such as electronics, pharmaceuticals, and research whereby they help maintain a clean environment by removing gaseous substances and floating solid particles.

This prevents harm to both the products being worked on and workers themselves.

The glove box filters include full-circumstance filtration, product discharge in an inert environment, drying, et cetera; some of them are custom-made to meet certain specifications.

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Filtration Glove Box

What are Filtration Glove Boxes?

A filtration glove box is a closed chamber for managing dangerous or delicate substances under controlled environment. It employs built-in filtration system such as HEPA filters to get rid of impurities that can affect users and materials. They are ordinarily seen in pharmaceutical or chemical powder producing labs, with many uses in microelectronics, optics, cell culture, medical devices, genomics, proteomics and cell biology amongst others. The Bionics Consortium glove box systems provide accurate atmosphere control and the containment of harmful substances.

Types of Filter in Glove-Boxes

The filtering types and sizes of glove box filters like HEPA and ULPA are different. While the HEPA captures bigger particles, the ULPA catches smaller ones at lower airflows. They last for 5 to 8 years.

Filtration glove boxes are used to safeguard both staff and products through the removal of airborne dusts and powders by employing HEPA or ULPA filtration. Commonly used at laboratories manufacturing pharmaceutical or chemical powders besides suitability for a range of applications such as optics, microelectronics, cell culture, medical devices and genomics. Such systems can be configured for either positive or negative pressure and come in open-loop, closed-loop, and adjustable-flow designs.

  • Adjustable flow filtered glove-box systems: Suitable for both open-loop and closed-loop circulation.
  • Closed loop filtration glove box system: Air continuously filtered inside the glove-box is re-circulated.
  • Open loop design: Including an inlet filter that captures micro-pollutants from external air
  • Single pass configurations: Filtering ambient air into enclosures once only; not appropriate for low-moisture/low-oxygen controlled gas atmospheres etc.

HEPA-filtered Glove Boxes

The glove box contains HEPA filters that serve as airtight barriers to protect the operator from harmful dust and particles in the air.

Glove Box Features

  • The lining is made of one-piece, durable polyethylene that can be cleaned easily.
  • Dry powder epoxy-coated steel superstructure for better resistance against corrosion.
  • 35 mm thick laminated safety glass viewing window for equipment loading.
  • Space-saving transfer chamber doors with quick-latches. Glove boxes have an enclosure with a floor-sealed black chemical-resistant work surface.
  • A blower, integrated with air flow adjustment speed varying from 13 CFM to 100 CFM Built-in blower with speed control for airflow from 13 CFM to 100 CFM.
  • Inlet and outlet HEPA filters for 99.99% efficiency.

This glove-box has applications in pharmaceutical research, nanotechnology, biochemistry, and cleanroom. It meets ISO Class 1 atmosphere containment conditions for oxygen leak rates and achieves ISO Class 3 conditions for airborne particulate cleanliness.

Static-Dissipative PVC Chamber

Drug powder introduction is achieved by means of the static-dissipative PVC chamber, which includes a mixing/packaging station and ultra-low penetration air filters to promote a low-humidity, static-safe environment. Sample transfer is accommodated through dual-sided air locks, while an automated nitrogen control system maintains a sub-ambient RH set point. As a result of this, ionising nozzles are provided to ensure that the process remains clean and free from static charges.

Applications of Filtered Glove Box

Its usage spans across various industries, such as:

  • Pharmaceutical and Biotech,
  • Chemical Research,
  • Electronics and Semiconductors,
  • Nuclear and radioactive material handling, among others.

Low-Humidity, Easy-Access Isolator

  • Space-saving corner installation
  • Dual pneumatically operated access doors
  • Gloved operators work in unique chambers
  • Humidity control system for sub-ambient humidity level
  • Closed-loop filtration system for process gas cleanliness
  • Diverter valve for 100% recirculation or partial exhausting

Medical Nano-Fibre Processing Chamber

  • Enables evaporation of volatile solvents that are used in medicine.
  • It needs low humidity (as low as 5% RH) and resistance to corrosive solvents.
  • Serves as a safe exhalation line for vapor removal.
  • Dry gas process micro-filtered to rid of contaminants.

Pharmaceutical Powder Packaging Glove Box

Dual HEPA filter open-loop filtration model which has the following characteristics:

  • Because of these features, chemotherapy powders as well as other dangerous substances can be packed and handled safely.
  • A HEPA filter draws air using a filter/fan unit.
  • Similarly, exhaust air is drawn out by another HEPA filter and then transported to a secondary filtration unit.
  • Filter port covers that permit Fine powder contamination-free handling.
  • Air lock on the right side for material passage.
  • Ease of scale loading through front swinging window sashes.

Anaerobic Test Chamber

  • Automated dual-level chamber for testing efficacy and dosage of drugs.
  • Maintains oxygen concentration at chosen temperature below 0.1%.
  • Computer-controlled electronic interlocks and rapid purging antechambers for sample transfer.
  • Prevents microbial contamination during sample or equipment extraction.
  • It features a touch-screen control panel, programmable presets, pneumatic doors, and rear access panels for equipment maintenance.

Product Features

The glove box filters include full-circumstance filtration, product discharge in an inert environment, drying, et cetera; some of them are custom-made to meet certain specifications.

Construction and Design

  • Single-piece moulded medium density polyethylene shell
  • Dry powder epoxy-coated steel superstructure
  • View window made out of 1/4″ thick laminated safety glass
  • Space-saving interior and exterior transfer chamber doors
  • Black chemical-resistant work surface
  • The interior ceiling-mounted electrical duplex receptacle (max. 5 amps)

Equipment and Features

  • They came with some Neoprene gloves.
  • It had a blower that was built in, and it had speed control.
  • The lamp used to be fluorescent (22 watts).
  • There is a separate set of integrated switches for the light, blower, and electrical receptacle.
  • HEPA filters for inlet and outlet that are 0.3 microns efficient at 99.99%
  • A gauge for the main chamber’s static pressure
  • Two internal interlocking shelves in the transfer chamber
  • The manufacturer tested it on leaks using a mass spectrometer.

Performance and Certifications

  • Exceed ISO Class 3 hygiene status but also meet the requirements of ISO Class 5
  • ETL listed /115 V models/; CE compliant /230 V models/.

Optional Accessories

The product includes an acrylic viewing window, Add-A-Valve Kit, Anti-Static Ioniser Fan, Balance Vibration Isolator, Blower Foot Switch, Complete Valve Set, Diaphragm Pumps, Electrical Power Strips, etc.

Filtration Glove Boxes Diagram

Simple-Closed-Loop
Multiconfig-Closed-Loop
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Bionics Consortium Pvt. Ltd. is a premier Indian company specializing in the manufacturing, supplying, and exporting of laboratory and scientific equipment, available in both standard and custom designs.

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